Automatic software for extracellular volume fraction mapping in the myocardium
نویسندگان
چکیده
Background CMR is a useful tool for myocardial tissue characterization and to assess fibrosis and edema non-invasively. The estimation of extracellular volume fraction (ECV) is emerging as accurate biomarkers in many cardiac diseases associated with diffuse myocardial fibrosis. In this work, we present our automatic tool for ECV map creation. All the computational system consists of an executable file developed in Matlab (Mathworks Inc.).
منابع مشابه
Cardiac T1 mapping in congenital heart disease: bolus versus infusion protocol for measurement of myocardial extracellular volume
Background Measurement of myocardial extracellular volume fraction (ECV) with T1 mapping cardiac magnetic resonance (CMR) before and after the application of a gadolinium-based extracellular contrast agent enables the assessment of diffuse myocardial fibrosis. The equilibrium between blood and myocardium contrast concentration required for ECV measurements can be achieved with a primed contrast...
متن کاملAge-corrected measurement of extracellular volume fraction in remote normal myocardium is correlated with extent of risk area in AMI patients
Background Reduction of post-contrast T1 in remote normal myocardium was recently reported in patients with AMI, indicating that extracellular matrix expansion occurs in remote myocardium early after MI. Such extracellular matrix expansion observed in non-infarcted myocardium without edema seems to be one of key factors causing LV remodeling after MI. However, since the previous study only dete...
متن کاملMyocardial extracellular volume fraction (ECV) measurements based on T1-mapping in healthy monozygotic twins - another similarity or rather disagreement in twins?
Background The T1-mapping MOLLI technique has already proved to be a robust and reproducible technique for myocardial extracellular volume fraction (ECV) estimation in both healthy individuals and patients with different cardiomyopathies. Monozygotic twins share the same DNA information and frequently grow up in a similar environment. However, epigenetic as well as environmental factors may lea...
متن کاملNon-invasive measurement of myocardial extracellular volume using T1 mapping as a novel biomarker of diffuse fibrosis in dilated cardiomyopathy
Background Diffuse myocardial fibrosis is frequently observed in histologies of dilated cardiomyopathy (DCM). T1-mapping techniques have the potential to measure fibrosis quantitatively and therefore provide novel cardiac magnetic resonance (CMR) insights into myocardial tissue characterization beyond the presently employed late gadolinium enhanced (LGE) techniques. Fibrosis results in expansio...
متن کاملUnderstanding why edema in salvaged myocardium is difficult to detect by late gadolinium enhancement
Background T2-weighted cardiac magnetic resonance (CMR) can visualize myocardial edema in salvaged myocardium which appears non-infarcted by late gadolinium enhancement (LGE) CMR. However, the mechanisms governing why LGE does not visualize edema in noninfarcted myocardium remain unclear. The objective of the study was to evaluate the extracellular volume fraction (ECV) of edematous salvaged my...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 17 شماره
صفحات -
تاریخ انتشار 2015